{"id":194104,"date":"2026-07-17T03:19:42","date_gmt":"2026-07-17T08:49:42","guid":{"rendered":"https:\/\/newslink360.space\/?p=194104"},"modified":"2026-07-17T03:19:42","modified_gmt":"2026-07-17T08:49:42","slug":"ferumoxytol-effective-contrast-agent-at-low-doses-emj","status":"publish","type":"post","link":"https:\/\/newslink360.space\/?p=194104","title":{"rendered":"Ferumoxytol Effective Contrast Agent at Low Doses \u2013 EMJ"},"content":{"rendered":"<p><br \/>\n<\/p>\n<div>\n<p>    FERUMOXYTOL may serve as an effective contrast agent in 3D whole-heart cardiovascular magnetic resonance (CMR) <a href=\"https:\/\/www.emjreviews.com\/radiology\/news\/cardiac-fetal-imaging-identifies-risk-in-newborns\/\" target=\"_blank\" rel=\"noopener\">imaging<\/a> in paediatric and young patients even at a dose of 1 mg\/kg, a new prospective study has found.<sup>1<\/sup><\/p>\n<h2><strong>3D Whole-Heart CMR and Ferumoxytol<\/strong><\/h2>\n<p>3D whole-heart imaging is a common CMR technique, widely adopted across clinical practice.<sup>2<\/sup><\/p>\n<p>Ferumoxytol is an intravenous iron supplement that is often used off-label as a contrast agent in CMR scans.<\/p>\n<p>Reported doses range from 1 mg\/kg to 7.5 mg\/kg.<sup>3<\/sup><\/p>\n<h2><strong>Measuring Image Quality<\/strong><\/h2>\n<p>Researchers examined 45 patients with <a href=\"https:\/\/www.emjreviews.com\/interventional-cardiology\/news\/stenting-outperforms-in-neonatal-congenital-heart-disease\/\" target=\"_blank\" rel=\"noopener\">congenital heart disease<\/a>, who underwent ferumoxytol-enhanced 3D whole-heart CMR using sequential dose regimens: 1 mg\/kg to 2 mg\/kg or 2 mg\/kg to 3 mg\/kg.<sup>1<\/sup><\/p>\n<p>They analysed right coronary artery image quality and visible length, contrast-to-noise ratio, image quality of the cardiac chambers and great vessels, and diagnostic completeness.<\/p>\n<h2><strong>No Differences Across 1 to 3 mg\/kg<\/strong><\/h2>\n<p>Across all doses, there were no significant differences observed in: contrast-to-noise ratio, right coronary artery length, image quality, or diagnostic completeness.<\/p>\n<h2><strong>Imaging Implications<\/strong><\/h2>\n<p>In patients with congenital heart disease, researchers reported, ferumoxytol-enhanced 3D whole-heart imaging provides robust diagnostic assessments across a range of contrast doses.<\/p>\n<p>Findings showed that reducing the ferumoxytol dose to as low as 1-2 mg\/kg does not compromise image quality, coronary artery visualisation, or overall diagnostic performance compared with higher doses of the contrast agent. The findings also support ongoing efforts to minimise contrast exposure while maintaining high-quality imaging for complex cardiovascular assessments.<\/p>\n<p>Overall, researchers reported, optimised low-dose ferumoxytol protocols could improve the efficiency and practicality of contrast-enhanced CMR in paediatric and adult patients with congenital health disease.<\/p>\n<p><strong>References<\/strong><\/p>\n<p><sup>1<\/sup> Erdem S et al. Ferumoxytol dose optimization for three-dimensional whole-heart magnetic resonance imaging in patients with congenital heart disease. Pediatr Radiol. 2026;DOI:10.1007\/s00247-026-06706-y.<\/p>\n<p><sup>2<\/sup> Greil G et al. 3D whole heart imaging for congenital heart disease. Front Pediatr. 2017;5:36.<\/p>\n<p><sup>3<\/sup> Vasanawala SS et al. Safety and technique of ferumoxytol administration for MRI. Magn Reson Med. 2016;75:2107\u20132111.<\/p>\n<p><em>Featured image:<\/em> <em>samunella on Adobe Stock<\/em><\/p>\n<\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/www.emjreviews.com\/cardiology\/news\/ferumoxytol-effective-contrast-agent-in-cmr-even-at-low-doses\/\" target=\"_blank\" rel=\"noopener\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>FERUMOXYTOL may serve as an effective contrast agent in 3D whole-heart cardiovascular magnetic resonance (CMR) imaging in paediatric and young patients even at a dose of 1 mg\/kg, a new prospective study has found.1 3D Whole-Heart CMR and Ferumoxytol 3D whole-heart imaging is a common CMR technique, widely adopted across clinical practice.2 Ferumoxytol is an&#8230;<\/p>\n","protected":false},"author":1,"featured_media":194105,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[7],"tags":[],"class_list":["post-194104","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-national-news"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/newslink360.space\/wp-content\/uploads\/2026\/07\/9am-radiology-4.jpg","jetpack_likes_enabled":true,"jetpack-related-posts":[{"id":198432,"url":"https:\/\/newslink360.space\/?p=198432","url_meta":{"origin":194104,"position":0},"title":"Delgocitinib Cream Improved Atopic Dermatitis","author":"Ajay Kumar Verma","date":"July 29, 2026","format":false,"excerpt":"DELGOCITINIB cream demonstrated dose dependent improvements in adults with mild to severe atopic dermatitis during an 8 week randomised Phase IIb trial, with greater efficacy observed at higher doses while maintaining a favourable safety profile. Dose Response Demonstrated Across Efficacy Endpoints Researchers evaluated the efficacy and safety of delgocitinib cream\u2026","rel":"","context":"In &quot;National News&quot;","block_context":{"text":"National News","link":"https:\/\/newslink360.space\/?cat=7"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/2pm-derm-7.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/2pm-derm-7.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/2pm-derm-7.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/2pm-derm-7.jpg?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":193833,"url":"https:\/\/newslink360.space\/?p=193833","url_meta":{"origin":194104,"position":1},"title":"\u091c\u0947\u090f\u0938\u0921\u092c\u094d\u0932\u094d\u092f\u0942 \u090f\u092e\u091c\u0940 \u092e\u094b\u091f\u0930 \u0928\u0947 \u092d\u093e\u0930\u0924 \u0915\u0947 \u092a\u0939\u0932\u0947 \u092e\u0932\u094d\u091f\u0940-\u090f\u0928\u0908\u0935\u0940 \u0906\u0930\u094d\u0915\u093f\u091f\u0947\u0915\u094d\u091a\u0930 \u0915\u093e \u0916\u0941\u0932\u093e\u0938\u093e \u0915\u093f\u092f\u093e; \u091a\u093e\u0930 \u092a\u094d\u0930\u0915\u093e\u0930 \u0915\u0947 \u0935\u093e\u0939\u0928\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u090f\u0915 \u092e\u0902\u091a","author":"Ajay Kumar Verma","date":"July 16, 2026","format":false,"excerpt":"JSW MG \u092e\u094b\u091f\u0930 \u0907\u0902\u0921\u093f\u092f\u093e \u0928\u0947 \u0917\u0941\u0930\u0941\u0935\u093e\u0930 \u0915\u094b MG ADAPT (\u090f\u0921\u0935\u093e\u0902\u0938\u094d\u0921 \u0921\u094d\u0930\u093e\u0907\u0935 \u0906\u0930\u094d\u0915\u093f\u091f\u0947\u0915\u094d\u091a\u0930 \u092a\u094d\u0932\u0947\u091f\u092b\u0949\u0930\u094d\u092e \u091f\u0947\u0915\u094d\u0928\u094b\u0932\u0949\u091c\u0940) \u0915\u093e \u0905\u0928\u093e\u0935\u0930\u0923 \u0915\u093f\u092f\u093e, \u091c\u093f\u0938\u0915\u0947 \u092c\u093e\u0930\u0947 \u092e\u0947\u0902 \u0909\u0938\u0915\u093e \u0915\u0939\u0928\u093e \u0939\u0948 \u0915\u093f \u092f\u0939 \u092d\u093e\u0930\u0924 \u0915\u093e \u092a\u0939\u0932\u093e \u092e\u0932\u094d\u091f\u0940-\u0928\u094d\u092f\u0942 \u090f\u0928\u0930\u094d\u091c\u0940 \u0935\u094d\u0939\u0940\u0915\u0932 (NEV) \u092a\u094d\u0932\u0947\u091f\u092b\u0949\u0930\u094d\u092e \u0939\u0948\u0964\u092e\u0949\u0921\u094d\u092f\u0942\u0932\u0930 \u0906\u0930\u094d\u0915\u093f\u091f\u0947\u0915\u094d\u091a\u0930 \u0915\u0902\u092a\u0928\u0940 \u0915\u0947 \u092d\u0935\u093f\u0937\u094d\u092f \u0915\u0947 \u0907\u0932\u0947\u0915\u094d\u091f\u094d\u0930\u093f\u0915 \u0935\u093e\u0939\u0928\u094b\u0902 (\u0908\u0935\u0940), \u0939\u093e\u0907\u092c\u094d\u0930\u093f\u0921 \u0907\u0932\u0947\u0915\u094d\u091f\u094d\u0930\u093f\u0915 \u0935\u093e\u0939\u0928\u094b\u0902 (\u090f\u091a\u0908\u0935\u0940), \u092a\u094d\u0932\u0917-\u0907\u0928 \u0939\u093e\u0907\u092c\u094d\u0930\u093f\u0921 \u0907\u0932\u0947\u0915\u094d\u091f\u094d\u0930\u093f\u0915 \u0935\u093e\u0939\u0928\u094b\u0902\u2026","rel":"","context":"In &quot;Auto News&quot;","block_context":{"text":"Auto News","link":"https:\/\/newslink360.space\/?cat=120"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/jsw-mg-motor-2026-07-0ea96c2921a5cfa6befa96713dd6fb9d.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/jsw-mg-motor-2026-07-0ea96c2921a5cfa6befa96713dd6fb9d.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/jsw-mg-motor-2026-07-0ea96c2921a5cfa6befa96713dd6fb9d.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/jsw-mg-motor-2026-07-0ea96c2921a5cfa6befa96713dd6fb9d.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/jsw-mg-motor-2026-07-0ea96c2921a5cfa6befa96713dd6fb9d.jpg?resize=1050%2C600&ssl=1 3x"},"classes":[]},{"id":196195,"url":"https:\/\/newslink360.space\/?p=196195","url_meta":{"origin":194104,"position":2},"title":"MG Motor launches premium editions of these two vehicles, only 50 customers will be able to buy them","author":"Ajay Kumar Verma","date":"July 23, 2026","format":false,"excerpt":"MG Select has recently launched Couture Editions of Cyberster and M9, which are limited editions. 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