{"id":195940,"date":"2026-07-23T06:56:24","date_gmt":"2026-07-23T12:26:24","guid":{"rendered":"https:\/\/newslink360.space\/?p=195940"},"modified":"2026-07-23T06:56:24","modified_gmt":"2026-07-23T12:26:24","slug":"glp-1-and-breast-cancer-survival-findings","status":"publish","type":"post","link":"https:\/\/newslink360.space\/?p=195940","title":{"rendered":"GLP-1 And Breast Cancer Survival Findings"},"content":{"rendered":"<p><br \/>\n<\/p>\n<div>\n<p>    <a href=\"https:\/\/www.emjreviews.com\/oncology\/news\/glp-1-agonists-linked-to-lower-breast-cancer-incidence\/\" target=\"_blank\" rel=\"noopener\">GLP-1<\/a> use after breast cancer diagnosis was associated with improved overall survival among patients with type 2 diabetes (T2D) in a retrospective cohort study examining post diagnosis exposure and mortality outcomes. The study investigated whether GLP-1 receptor agonists (GLP-1RA) influenced survival among women with T2D and breast cancer, with findings suggesting a lower risk of overall mortality among exposed patients.<\/p>\n<h2><strong>GLP-1 Exposure and Survival Outcomes<\/strong><\/h2>\n<p>Researchers conducted a single institution, propensity score matched, 2 year landmark retrospective study involving women with T2D who were diagnosed with breast cancer at City of Hope between 2009 and 2025. Patients were categorised according to whether they had post diagnosis exposure to GLP-1RA.<\/p>\n<p>The analysis included 226 matched pairs. Patients were compared using statistical methods including t tests for continuous variables, chi square tests for categorical variables, multivariable Cox proportional hazards models for overall mortality risk, and Kaplan\u2013Meier survival analysis.<\/p>\n<h2><strong>Mortality Risk Findings<\/strong><\/h2>\n<p>The data were associated with a lower risk of overall mortality among patients exposed to GLP-1RA. During follow up, there were 47 deaths, including 30 deaths among patients without exposure and 17 deaths among patients with exposure.<\/p>\n<p>Multivariable analysis showed that GLP-1RA exposure was associated with a reduced overall mortality risk (hazard ratio: 0.51; 95% CI: 0.28\u20130.93; p=0.03). A sensitivity analysis limited to patients with stage I to III disease showed similar findings (hazard ratio: 0.45; 95% CI: 0.23\u20130.85; p=0.03).<\/p>\n<p>Kaplan\u2013Meier survival analysis also demonstrated an association between GLP-1RA exposure and increased overall survival (log-rank p=0.02).<\/p>\n<h2><strong>Future Clinical Considerations<\/strong><\/h2>\n<p>The findings suggested that GLP-1RA use after breast cancer diagnosis may be associated with improved overall survival among patients with T2D. However, the study assessed all cause mortality and did not distinguish between cancer-specific and non-cancer causes of death.<\/p>\n<p>Further investigation will be needed to better understand the relationship between GLP-1RA exposure, breast cancer outcomes, and mortality patterns.<\/p>\n<h2><strong>Reference<\/strong><\/h2>\n<p>Nelson RA et al. GLP-1 receptor agonist use and overall survival among women with type 2 diabetes and breast cancer: a retrospective cohort study. Oncologist. 2026;oyag268.<\/p>\n<p><em>Featured Image: Shutterly on Adobe Stock<\/em><\/p>\n<p>\u00a0<\/p>\n<\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/www.emjreviews.com\/diabetes\/news\/glp-1-use-linked-to-breast-cancer-survival-in-patients-with-diabetes\/\" target=\"_blank\" rel=\"noopener\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>GLP-1 use after breast cancer diagnosis was associated with improved overall survival among patients with type 2 diabetes (T2D) in a retrospective cohort study examining post diagnosis exposure and mortality outcomes. The study investigated whether GLP-1 receptor agonists (GLP-1RA) influenced survival among women with T2D and breast cancer, with findings suggesting a lower risk of&#8230;<\/p>\n","protected":false},"author":1,"featured_media":195941,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[7],"tags":[],"class_list":["post-195940","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-national-news"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/newslink360.space\/wp-content\/uploads\/2026\/07\/Diab-4pm.jpg","jetpack_likes_enabled":true,"jetpack-related-posts":[{"id":195831,"url":"https:\/\/newslink360.space\/?p=195831","url_meta":{"origin":195940,"position":0},"title":"EHA 2026 Abstract Highlights &#8211; European Medical Journal","author":"Ajay Kumar Verma","date":"July 23, 2026","format":false,"excerpt":"These abstracts highlight some of the cutting-edge research presented at the European Hematology Association (EHA) 2026 Congress. Covering topics ranging from liquid biopsy and cardiovascular risk to pregnancy complications and rare inherited blood disorders, the findings showcase emerging advances that could influence future diagnosis, risk stratification, and patient management across\u2026","rel":"","context":"In &quot;National News&quot;","block_context":{"text":"National News","link":"https:\/\/newslink360.space\/?cat=7"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/Hema-14.1-Congress-Review-thumbnail.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/Hema-14.1-Congress-Review-thumbnail.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/Hema-14.1-Congress-Review-thumbnail.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/Hema-14.1-Congress-Review-thumbnail.jpg?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":195897,"url":"https:\/\/newslink360.space\/?p=195897","url_meta":{"origin":195940,"position":1},"title":"Pediatric Surgical Site Infections and Language","author":"Ajay Kumar Verma","date":"July 23, 2026","format":false,"excerpt":"PEDIATRIC surgical site infections were linked to language differences and substantially greater hospitalization and readmission burdens. Researchers examining gastrointestinal surgery in children found that those who developed an infection were more likely to speak a primary language other than English or Spanish. The findings also questioned whether infection models built\u2026","rel":"","context":"In &quot;National News&quot;","block_context":{"text":"National News","link":"https:\/\/newslink360.space\/?cat=7"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/AdobeStock_271210313.jpeg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/AdobeStock_271210313.jpeg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/AdobeStock_271210313.jpeg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/AdobeStock_271210313.jpeg?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":197893,"url":"https:\/\/newslink360.space\/?p=197893","url_meta":{"origin":195940,"position":2},"title":"PCV-VG Ventilation Mode Improved Lung Mechanics","author":"Ajay Kumar Verma","date":"July 27, 2026","format":false,"excerpt":"A study found that a specific ventilation mode protects the lungs during surgery better than traditional methods, though clinical outcomes remained similar. RT\u2019s Three Key Takeaways: Improved Respiratory Mechanics: Patients receiving pressure control-volume guarantee (PCV-VG) ventilation demonstrated higher respiratory system compliance and lower driving pressure compared to those on volume\u2026","rel":"","context":"In &quot;National News&quot;","block_context":{"text":"National News","link":"https:\/\/newslink360.space\/?cat=7"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/patient-on-ventilator-hospital.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/patient-on-ventilator-hospital.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/patient-on-ventilator-hospital.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/patient-on-ventilator-hospital.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/patient-on-ventilator-hospital.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/patient-on-ventilator-hospital.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":193254,"url":"https:\/\/newslink360.space\/?p=193254","url_meta":{"origin":195940,"position":3},"title":"Interview: Christopher Cogle &#8211; European Medical Journal","author":"Ajay Kumar Verma","date":"July 14, 2026","format":false,"excerpt":"Your work spans clinical oncology, stem cell biology, public health leadership, and healthcare policy. How have those different domains influenced the way you think about cancer care, not simply as treatment, but as a systems-level challenge involving access, prevention, and long-term outcomes? Moving back and forth among the bedside, the\u2026","rel":"","context":"In &quot;National News&quot;","block_context":{"text":"National News","link":"https:\/\/newslink360.space\/?cat=7"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/Chris-cogle_Video.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/Chris-cogle_Video.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/Chris-cogle_Video.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/Chris-cogle_Video.jpg?resize=700%2C400&ssl=1 2x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/Chris-cogle_Video.jpg?resize=1050%2C600&ssl=1 3x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/Chris-cogle_Video.jpg?resize=1400%2C800&ssl=1 4x"},"classes":[]},{"id":197749,"url":"https:\/\/newslink360.space\/?p=197749","url_meta":{"origin":195940,"position":4},"title":"Ventilation Mode Improves Lung Mechanics in Surgery","author":"Ajay Kumar Verma","date":"July 27, 2026","format":false,"excerpt":"Pressure control-volume guarantee (PCV-VG) ventilation improved intraoperative respiratory mechanics but did not significantly reduce postoperative pulmonary complications (PPCs) compared with conventional volume control ventilation (VCV) in patients undergoing emergency abdominal surgery, according to a randomized controlled trial. Patients undergoing emergency laparotomy are at high risk of developing postoperative pulmonary complications,\u2026","rel":"","context":"In &quot;National News&quot;","block_context":{"text":"National News","link":"https:\/\/newslink360.space\/?cat=7"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/AdobeStock_168115298.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/AdobeStock_168115298.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/AdobeStock_168115298.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/AdobeStock_168115298.jpg?resize=700%2C400&ssl=1 2x"},"classes":[]},{"id":194765,"url":"https:\/\/newslink360.space\/?p=194765","url_meta":{"origin":195940,"position":5},"title":"Anaemia, alcohol major risk factors behind brain clots, finds ICMR study","author":"Ajay Kumar Verma","date":"July 19, 2026","format":false,"excerpt":"Anaemia and alcohol consumption have emerged among the leading risk factors of cerebral venous thrombosis (CVT), in contrast to Western studies where hormonal and genetic factors such as abnormal clotting of blood predominate, said an Indian Council of Medical Research-National Institute of Non-communicable Disease Epidemiology (ICMR-NINE).The CVT is a type\u2026","rel":"","context":"In &quot;National News&quot;","block_context":{"text":"National News","link":"https:\/\/newslink360.space\/?cat=7"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/1784499663_high.jpg?resize=350%2C200&ssl=1","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/1784499663_high.jpg?resize=350%2C200&ssl=1 1x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/1784499663_high.jpg?resize=525%2C300&ssl=1 1.5x, https:\/\/i0.wp.com\/newslink360.space\/wp-content\/uploads\/2026\/07\/1784499663_high.jpg?resize=700%2C400&ssl=1 2x"},"classes":[]}],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/pgnRh4-OYk","_links":{"self":[{"href":"https:\/\/newslink360.space\/index.php?rest_route=\/wp\/v2\/posts\/195940","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newslink360.space\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/newslink360.space\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/newslink360.space\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/newslink360.space\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=195940"}],"version-history":[{"count":0,"href":"https:\/\/newslink360.space\/index.php?rest_route=\/wp\/v2\/posts\/195940\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/newslink360.space\/index.php?rest_route=\/wp\/v2\/media\/195941"}],"wp:attachment":[{"href":"https:\/\/newslink360.space\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=195940"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/newslink360.space\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=195940"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/newslink360.space\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=195940"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}